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yycI [2017-11-10 15:02:03]
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yycI [2017-11-10 15:02:03]

negative effector of WalK, controls cell wall metabolism
locus
BSU40380
pI
5.28
mw
32.44 kDa
protein length
280 aa Sequence Blast
gene length
840 bp Sequence Blast
function
control of cell wall metabolism
product
negative effector of WalK
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.5|Cell wall/ other]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.2|Control of two-component response regulators] → [category|SW 3.4.2.2.3|Control of response regulators/ other]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    4,149,667 → 4,150,509

    The protein

    Structure

  • [PDB|2O3O], [Pubmed|17307848]

    • [SW|Localization]

  • cell membrane (according to Swiss-Prot), spotty close to the membrane [Pubmed|21219466]

    • Expression and Regulation

    Operons

    genes
    [gene|7F340423A34CE40D1F1AA8D373F7C4B859A6496D|walR]-[gene|E88978809272FAC2520DB4ABCA0554F8028F3451|walK]-[gene|06D2D03C65D50E3909B2C93835193815B6016967|walH]-[gene|EE681C9A42FCC29CBB55CC9566EE4CFF986D0F1D|walI]-[gene|D5321F707E183E72B225F1CED2F2FDCB1183B88A|walJ]-[gene|75B8C37E589C855D2BAD7FB51B9600E161ACFBD3|htrC]
    description
    [Pubmed|9829949]

    regulation

  • ''htrC'' transcript expressed during sporulation [Pubmed|9829949]
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    Biological materials

    Mutant

  • MGNA-B825 (yycI::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1824 NBRP B. subtilis, Japan]
  • BKE40380 (Δ[gene|EE681C9A42FCC29CBB55CC9566EE4CFF986D0F1D|walI]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE40380 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GGCAACGATGAAGATTGATT, downstream forward: _UP4_TGAAAATAATGGAGTGAGAC
  • BKK40380 (Δ[gene|EE681C9A42FCC29CBB55CC9566EE4CFF986D0F1D|walI]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK40380 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GGCAACGATGAAGATTGATT, downstream forward: _UP4_TGAAAATAATGGAGTGAGAC

    • References

  • 17307850,17350627,17307848,9829949,18408157,21219466